Epididymis-specific lipocalin promoters

Epididymis-specific lipocalin promoters.

Our goal is to decipher which DNA sequences are required for tissue-specific expression of epididymal genes. At least 6 epididymis-specific lipocalin genes are known. These are differently regulated and regionalized in the epididymis. Lipocalin 5 (Lcn5 or mE-RABP) and Lipocalin 8 (Lcn8 or mEP17) are homologous genes belonging to the epididymis-specific lipocalin gene cluster. Both the 5 kb prom...

Novel androgen-dependent promoters direct expression of the C4b-binding protein alpha-chain gene in epididymis.

C4b-binding protein (C4BP) is a large plasma protein composed of seven alpha-chains and one beta-chain and is involved in the fluid phase regulation of the classical pathway of the complement system. Complement inhibitory activity is located in the alpha-chain, and its mRNA has been detected only in liver to date. Here, we have isolated cDNA clones encoding the alpha-chain of guinea pig C4BP (C...

Novel Androgen-Dependent Promoters Direct Expression of the C4b-Binding Protein a-Chain Gene in Epididymis

Trichome Specific Expression: Promoters and Their Applications

As often reminded to the readers in articles or reviews which deal with plant adaptation to their environment, higher plants are sessile organisms, a life habit which does not allow them to escape danger or to move to avoid adverse conditions. This environmental pressure has led to a myriad of adaptations, which are reflected in the vast diversity of plant habitats, morphologies, life cycles an...

Identification and characterization of an epididymis-specific gene, Ces7.

Carboxylesterases (CEs) represent a multigene family of serine-dependent enzymes. Male-dependent CEs are over-expressed in the male reproductive tract of different animal species (bivalve mollusks, fruit-flies, and mammals). Here, a novel rat epididymis-specific gene named Ces7 was cloned and characterized. It was a novel member of CE family, which was mainly expressed and secreted to the lumen...